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CARCINOMA
La mayoría de pacientes no tendrá una fuente primaria definible. Para tales pacientes, una variedad de enfoques de poliquimioterapia han sido tratados con poco éxito. Ningún tratamiento puede considerarse estándar en el presente. Por lo tanto, tales pacientes deben considerarse en ensayos clínicos disponibles. LECTURAS RECOMENDADAS Muir C: Cancer of unknown primary site. Cancer 75(1): 353-356, 1995. Briasoulis E, Pavlidis N: Cancer of unknown primary origin. The Oncologist 2(3): 142-152, 1997. Hainsworth JD, Greco FA: Treatment of patients with cancer of an unknown primary site. New England Journal of Medicine 329(4): 257-263, 1993. Neumann KH, Nystrom JS: Metastatic cancer of unknown origin: nonsquamous cell type. Seminars in Oncology 9(4): 427-434, 1982. Moertel CG, Reitemeier RJ, Schutt AJ, et al. : Treatment of the patient with adenocarcinoma of unknown origin. Cancer 30(6): 1469-1472, 1972. Altman E, Cadman E: An analysis of 1539 patients with cancer of unknown primary site. Cancer 57(1): 120-124, 1986. Abbruzzese JL, Abbruzzese MC, Hess KR, et al. : Unknown primary carcinoma: natural history and prognostic factors in 657 consecutive patients. Journal of Clinical Oncology 12(6): 1272-1280, 1994. Haskell CM, Cochran AJ, Barsky SH, et al. : Metastasis of unknown origin. Current Problems in Cancer 12(1): 1-58, 1988. Ruddon RW, Norton SE: Use of biological markers in the diagnosis of cancers of unknown primary tumor. Seminars in Oncology 20(3): 251-260, 1993. Mackay B, Ordonez NG: Pathological evaluation of neoplasms with unknown primary tumor site. Seminars in Oncology 20(3): 206-228, 1993. Greco FA, Hainsworth JD: Cancer of unknown primary site. In: DeVita VT Jr, Hellman S, Rosenberg SA, eds. : Cancer: Principles and Practice of Oncology. Philadelphia, Pa: Lippincott-Raven Publishers, 5th ed. , 1997, pp 2423-2443. Motzer RJ, Rodriguez E, Reuter VE, et al. : Molecular and cytogenetic studies in the diagnosis of patients with poorly differentiated carcinomas of unknown primary site. Journal of Clinical Oncology 13(1): 274-282, 1995. Bosl GJ, Ilson DH, Rodriguez E, et al. : Clinical relevance of the i(12p) marker chromosome in germ cell tumors. Journal of the National Cancer Institute 86(5): 349-355, 1994. Hainsworth JD, Johnson DH, Greco FA: Poorly differentiated neuroendocrine carcinoma of unknown primary site: a newly recognized clinicopathologic entity. Annals of Internal Medicine 109(5): 364-371, 1988. Karsell PR, Sheedy PF, O'Connell MJ: Computed tomography in search of cancer of unknown origin. JAMA: Journal of the American Medical Association 248(3): 340-343, 1982. Greco FA, Burris HA, Erland JB, et al. : Carcinoma of unknown primary site: long term follow-up after treatment with paclitaxel, carboplatin, and etoposide. Cancer 89(12): 2655-2660, 2000.
Autor: FUNDACION SANTAFE DE BOGOTA
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